To explain all nature is too difficult a task for any one man or even for any one age. Tis much better to do a little with certainty & leave the rest for others that come after than to explain all things by conjecture without making sure of any thing.
Humans may crave absolute certainty; they may aspire to it; they may pretend, as partisans of certain religions do, to have attained it. But the history of science — by far the most successful claim to knowledge accessible to humans teaches that the most we can hope for is successive improvement in our understanding, learning from our mistakes, an asymptotic approach to the Universe, but with the proviso that absolute certainty will always elude us. We will always be mired in error. The most each generation can hope for is to reduce the error bars a little, and to add to the body of data to which error bars apply.
As mathematical and absolute certainty is seldom to be attained in human affairs, reasoning and public utility require that judges and all mankind in forming their opinion of the truth of facts should be regulated by the superior number of probabilities on the one side or the other
The fact is there is nothing that you can trust; and that is a terrible fact, whether you like it or not. Psychologically, there is nothing in the world that you can put your faith, your trust, or your belief in. Neither your gods, nor your science can save you, can bring you psychological certainty; and you have to accept that you can trust in absolutely nothing. That is a scientific fact, as well as a psychological fact. Because, your leaders — religious and political — and your books — sacred and profane — have all failed, and you are still confused, in misery, in conflict. So, that is an absolute, undeniable fact.